Does METHOTREXATE Cause Vasculitis? 494 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 494 reports of Vasculitis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.2% of all adverse event reports for METHOTREXATE.
494
Reports of Vasculitis with METHOTREXATE
0.2%
of all METHOTREXATE reports
24
Deaths
273
Hospitalizations
How Dangerous Is Vasculitis From METHOTREXATE?
Of the 494 reports, 24 (4.9%) resulted in death, 273 (55.3%) required hospitalization, and 22 (4.5%) were considered life-threatening.
Is Vasculitis Listed in the Official Label?
Yes, Vasculitis is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Vasculitis?
PREDNISONE (754)
APIXABAN (645)
RITUXIMAB (600)
ALBUTEROL (519)
LEVOTHYROXINE (475)
HYDROCHLOROTHIAZIDE (471)
ADALIMUMAB (461)
CANDESARTAN (434)
MEPOLIZUMAB (430)
AZATHIOPRINE (402)
Which METHOTREXATE Alternatives Have Lower Vasculitis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA