Does MITOTANE Cause Cardiotoxicity? 5 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5 reports of Cardiotoxicity have been filed in association with MITOTANE (Lysodren). This represents 0.5% of all adverse event reports for MITOTANE.
5
Reports of Cardiotoxicity with MITOTANE
0.5%
of all MITOTANE reports
4
Deaths
0
Hospitalizations
How Dangerous Is Cardiotoxicity From MITOTANE?
Of the 5 reports, 4 (80.0%) resulted in death.
Is Cardiotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MITOTANE. However, 5 reports have been filed with the FAERS database.
What Other Side Effects Does MITOTANE Cause?
Nausea (210)
Fatigue (205)
Off label use (154)
Diarrhoea (123)
Vomiting (97)
Drug ineffective (86)
Decreased appetite (77)
Adrenal insufficiency (76)
Dizziness (76)
Asthenia (70)
What Other Drugs Cause Cardiotoxicity?
DOXORUBICIN (1,366)
CYCLOPHOSPHAMIDE (1,009)
TRASTUZUMAB (950)
VINCRISTINE (446)
FLUOROURACIL (425)
RITUXIMAB (389)
ETOPOSIDE (366)
CAPECITABINE (307)
TOCILIZUMAB (278)
PREDNISONE (277)
Which MITOTANE Alternatives Have Lower Cardiotoxicity Risk?
MITOTANE vs MITOXANTRONE
MITOTANE vs MITRAGYNINE\HERBALS
MITOTANE vs MIZORIBINE
MITOTANE vs MOBOCERTINIB
MITOTANE vs MOCLOBEMIDE