Does NINTEDANIB Cause Agranulocytosis? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Agranulocytosis have been filed in association with NINTEDANIB. This represents 0.1% of all adverse event reports for NINTEDANIB.
15
Reports of Agranulocytosis with NINTEDANIB
0.1%
of all NINTEDANIB reports
4
Deaths
12
Hospitalizations
How Dangerous Is Agranulocytosis From NINTEDANIB?
Of the 15 reports, 4 (26.7%) resulted in death, 12 (80.0%) required hospitalization, and 10 (66.7%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NINTEDANIB. However, 15 reports have been filed with the FAERS database.
What Other Side Effects Does NINTEDANIB Cause?
Diarrhoea (9,103)
Nausea (4,198)
Dyspnoea (3,080)
Decreased appetite (2,832)
Death (2,790)
Weight decreased (2,628)
Vomiting (2,524)
Fatigue (2,511)
Cough (2,193)
Idiopathic pulmonary fibrosis (1,905)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which NINTEDANIB Alternatives Have Lower Agranulocytosis Risk?
NINTEDANIB vs NINTEDANIB ESYLATE
NINTEDANIB vs NIRAPARIB
NINTEDANIB vs NIRMATRELVIR\RITONAVIR
NINTEDANIB vs NIROGACESTAT
NINTEDANIB vs NIROGACESTAT HYDROBROMIDE