Does PACLITAXEL Cause Agranulocytosis? 243 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 243 reports of Agranulocytosis have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.3% of all adverse event reports for PACLITAXEL.
243
Reports of Agranulocytosis with PACLITAXEL
0.3%
of all PACLITAXEL reports
27
Deaths
150
Hospitalizations
How Dangerous Is Agranulocytosis From PACLITAXEL?
Of the 243 reports, 27 (11.1%) resulted in death, 150 (61.7%) required hospitalization, and 78 (32.1%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 243 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which PACLITAXEL Alternatives Have Lower Agranulocytosis Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON