Does PANITUMUMAB Cause Agranulocytosis? 10 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 10 reports of Agranulocytosis have been filed in association with PANITUMUMAB (Vectibix). This represents 0.1% of all adverse event reports for PANITUMUMAB.
10
Reports of Agranulocytosis with PANITUMUMAB
0.1%
of all PANITUMUMAB reports
4
Deaths
5
Hospitalizations
How Dangerous Is Agranulocytosis From PANITUMUMAB?
Of the 10 reports, 4 (40.0%) resulted in death, 5 (50.0%) required hospitalization, and 5 (50.0%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PANITUMUMAB. However, 10 reports have been filed with the FAERS database.
What Other Side Effects Does PANITUMUMAB Cause?
Rash (1,392)
Diarrhoea (1,123)
Death (767)
Dermatitis acneiform (758)
Neutropenia (757)
Skin toxicity (728)
Neuropathy peripheral (613)
Hypomagnesaemia (611)
Nausea (608)
Disease progression (600)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which PANITUMUMAB Alternatives Have Lower Agranulocytosis Risk?
PANITUMUMAB vs PANOBINOSTAT
PANITUMUMAB vs PANTOPRAZOLE
PANITUMUMAB vs PANTOPRAZOLE ANHYDROUS
PANITUMUMAB vs PANTOTHENIC ACID
PANITUMUMAB vs PAPAVERINE