PEGASPARGASE for Leukaemia: Side Effects & Safety Data
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There are 104 adverse event reports in the FDA FAERS database where PEGASPARGASE was used for Leukaemia.
Most Reported Side Effects for PEGASPARGASE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Febrile neutropenia | 1,589 | 13.8% | 75 | 1,427 |
| Pyrexia | 706 | 6.1% | 84 | 639 |
| Febrile bone marrow aplasia | 668 | 5.8% | 3 | 632 |
| Sepsis | 548 | 4.8% | 158 | 416 |
| Vomiting | 530 | 4.6% | 53 | 414 |
| Neutropenia | 521 | 4.5% | 84 | 391 |
| Abdominal pain | 469 | 4.1% | 60 | 369 |
| Hypertriglyceridaemia | 399 | 3.5% | 29 | 179 |
| Hypotension | 388 | 3.4% | 114 | 323 |
| Thrombocytopenia | 382 | 3.3% | 59 | 269 |
| Nausea | 370 | 3.2% | 22 | 316 |
| Pancreatitis | 358 | 3.1% | 34 | 259 |
| Pneumonia | 353 | 3.1% | 173 | 192 |
| Hyperbilirubinaemia | 349 | 3.0% | 33 | 145 |
| Off label use | 347 | 3.0% | 72 | 166 |
Other Indications for PEGASPARGASE
Acute lymphocytic leukaemia (6,611)
B precursor type acute leukaemia (531)
Product used for unknown indication (448)
B-cell type acute leukaemia (374)
T-cell type acute leukaemia (297)
Chemotherapy (192)
Acute lymphocytic leukaemia recurrent (172)
Angiocentric lymphoma (163)
T-cell lymphoma (99)
Precursor t-lymphoblastic lymphoma/leukaemia (96)
Other Drugs Used for Leukaemia
DASATINIB (654)
VENETOCLAX (307)
CYTARABINE (288)
METHOTREXATE (282)
IMATINIB (281)
RUXOLITINIB (230)
NILOTINIB (203)
BOSUTINIB (191)
VINCRISTINE (172)
CYCLOPHOSPHAMIDE (153)