Does PEGASPARGASE Cause Cardiac failure? 45 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 45 reports of Cardiac failure have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.4% of all adverse event reports for PEGASPARGASE.
45
Reports of Cardiac failure with PEGASPARGASE
0.4%
of all PEGASPARGASE reports
24
Deaths
30
Hospitalizations
How Dangerous Is Cardiac failure From PEGASPARGASE?
Of the 45 reports, 24 (53.3%) resulted in death, 30 (66.7%) required hospitalization, and 9 (20.0%) were considered life-threatening.
Is Cardiac failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 45 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Cardiac failure?
SACUBITRIL\VALSARTAN (4,504)
FUROSEMIDE (1,841)
APIXABAN (1,575)
CYCLOPHOSPHAMIDE (1,514)
DOXORUBICIN (1,367)
ADALIMUMAB (1,278)
DEXAMETHASONE (1,271)
TREPROSTINIL (1,168)
BISOPROLOL (1,159)
LENALIDOMIDE (1,115)
Which PEGASPARGASE Alternatives Have Lower Cardiac failure Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ