Does PEGASPARGASE Cause Cytopenia? 48 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 48 reports of Cytopenia have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.4% of all adverse event reports for PEGASPARGASE.
48
Reports of Cytopenia with PEGASPARGASE
0.4%
of all PEGASPARGASE reports
14
Deaths
23
Hospitalizations
How Dangerous Is Cytopenia From PEGASPARGASE?
Of the 48 reports, 14 (29.2%) resulted in death, 23 (47.9%) required hospitalization, and 12 (25.0%) were considered life-threatening.
Is Cytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 48 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Cytopenia?
RITUXIMAB (1,372)
LENALIDOMIDE (1,252)
DEXAMETHASONE (1,193)
CYCLOPHOSPHAMIDE (1,191)
VENETOCLAX (1,019)
METHOTREXATE (955)
ETOPOSIDE (854)
CARBOPLATIN (754)
DOXORUBICIN (709)
VINCRISTINE (648)
Which PEGASPARGASE Alternatives Have Lower Cytopenia Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ