Does PEGASPARGASE Cause Fluid overload? 38 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 38 reports of Fluid overload have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.3% of all adverse event reports for PEGASPARGASE.
38
Reports of Fluid overload with PEGASPARGASE
0.3%
of all PEGASPARGASE reports
15
Deaths
37
Hospitalizations
How Dangerous Is Fluid overload From PEGASPARGASE?
Of the 38 reports, 15 (39.5%) resulted in death, 37 (97.4%) required hospitalization, and 3 (7.9%) were considered life-threatening.
Is Fluid overload Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 38 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Fluid overload?
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (3,883)
TREPROSTINIL (1,239)
DIANEAL LOW (831)
MACITENTAN (809)
AMBRISENTAN (764)
EPOPROSTENOL (496)
CALCIUM\ICODEXTRIN\MAGNESIUM\SODIUM\SODIUM (493)
SELEXIPAG (294)
RIOCIGUAT (198)
BOSENTAN (168)
Which PEGASPARGASE Alternatives Have Lower Fluid overload Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ