Does PEGASPARGASE Cause Fungal sepsis? 17 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 17 reports of Fungal sepsis have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.2% of all adverse event reports for PEGASPARGASE.
17
Reports of Fungal sepsis with PEGASPARGASE
0.2%
of all PEGASPARGASE reports
13
Deaths
7
Hospitalizations
How Dangerous Is Fungal sepsis From PEGASPARGASE?
Of the 17 reports, 13 (76.5%) resulted in death, 7 (41.2%) required hospitalization, and 2 (11.8%) were considered life-threatening.
Is Fungal sepsis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 17 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Fungal sepsis?
DEXAMETHASONE (57)
TACROLIMUS (55)
METHOTREXATE (51)
MYCOPHENOLATE MOFETIL (42)
CYCLOPHOSPHAMIDE (40)
VANCOMYCIN (38)
CYTARABINE (36)
FLUDARABINE (34)
VINCRISTINE (33)
ETOPOSIDE (32)
Which PEGASPARGASE Alternatives Have Lower Fungal sepsis Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ