Fungal sepsis: Which Medications Cause It? (489 Reports Across 80 Drugs)
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Fungal sepsis has been reported as an adverse event with 80 different drugs in the FDA's FAERS database, with 489 total reports. 293 of these reports resulted in death.The drugs most commonly associated with Fungal sepsis are DEXAMETHASONE, TACROLIMUS, and METHOTREXATE.
489
Total Reports
80
Drugs Involved
293
Deaths
236
Hospitalizations
50.0 yrs
Average Patient Age
52.8% / 47.2%
Female / Male
Which Drugs Cause Fungal sepsis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| DEXAMETHASONE | 57 | 0.1% | 52 | 14 | 21 |
| TACROLIMUS | 55 | 0.1% | 46 | 23 | 10 |
| METHOTREXATE | 51 | 0.0% | 29 | 22 | 13 |
| MYCOPHENOLATE MOFETIL | 42 | 0.1% | 35 | 11 | 3 |
| CYCLOPHOSPHAMIDE | 40 | 0.0% | 30 | 12 | 12 |
| VANCOMYCIN | 38 | 0.1% | 18 | 16 | 9 |
| CYTARABINE | 36 | 0.1% | 22 | 25 | 11 |
| FLUDARABINE | 34 | 0.1% | 29 | 9 | 13 |
| VINCRISTINE | 33 | 0.1% | 28 | 8 | 2 |
| ETOPOSIDE | 32 | 0.1% | 26 | 11 | 11 |
| METHYLPREDNISOLONE | 32 | 0.1% | 27 | 8 | 7 |
| MEROPENEM | 31 | 0.2% | 22 | 15 | 6 |
| PREDNISOLONE | 30 | 0.0% | 21 | 10 | 4 |
| PREDNISONE | 29 | 0.0% | 12 | 19 | 9 |
| RITUXIMAB | 27 | 0.0% | 13 | 10 | 6 |
| DOXORUBICIN | 26 | 0.0% | 25 | 2 | 1 |
| ADALIMUMAB | 21 | 0.0% | 1 | 13 | 6 |
| FLUCONAZOLE | 21 | 0.1% | 16 | 4 | 1 |
| CEFTAZIDIME | 20 | 0.6% | 8 | 0 | 0 |
| CASPOFUNGIN | 18 | 0.5% | 17 | 7 | 0 |