Does PEGASPARGASE Cause Hypogonadism? 13 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 13 reports of Hypogonadism have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.1% of all adverse event reports for PEGASPARGASE.
13
Reports of Hypogonadism with PEGASPARGASE
0.1%
of all PEGASPARGASE reports
0
Deaths
1
Hospitalizations
How Dangerous Is Hypogonadism From PEGASPARGASE?
Of the 13 reports, 1 (7.7%) required hospitalization, and 13 (100.0%) were considered life-threatening.
Is Hypogonadism Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 13 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Hypogonadism?
FINASTERIDE (264)
OXYCODONE (40)
PROPECIA (35)
METHOTREXATE (32)
CYCLOPHOSPHAMIDE (29)
ACETAMINOPHEN\HYDROCODONE (26)
TESTOSTERONE (25)
ACETAMINOPHEN\OXYCODONE (24)
DENOSUMAB (24)
MORPHINE (24)
Which PEGASPARGASE Alternatives Have Lower Hypogonadism Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ