Does PEGASPARGASE Cause Lactic acidosis? 55 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 55 reports of Lactic acidosis have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.5% of all adverse event reports for PEGASPARGASE.
55
Reports of Lactic acidosis with PEGASPARGASE
0.5%
of all PEGASPARGASE reports
36
Deaths
53
Hospitalizations
How Dangerous Is Lactic acidosis From PEGASPARGASE?
Of the 55 reports, 36 (65.5%) resulted in death, 53 (96.4%) required hospitalization, and 7 (12.7%) were considered life-threatening.
Is Lactic acidosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 55 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Lactic acidosis?
METFORMIN (16,316)
AMLODIPINE (886)
LINEZOLID (824)
FUROSEMIDE (698)
ACETAMINOPHEN (561)
METFORMIN\SITAGLIPTIN (557)
ALBUTEROL (467)
EMPAGLIFLOZIN (434)
RAMIPRIL (430)
BISOPROLOL (425)
Which PEGASPARGASE Alternatives Have Lower Lactic acidosis Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ