Does PEGASPARGASE Cause Left ventricular dysfunction? 30 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 30 reports of Left ventricular dysfunction have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.3% of all adverse event reports for PEGASPARGASE.
30
Reports of Left ventricular dysfunction with PEGASPARGASE
0.3%
of all PEGASPARGASE reports
5
Deaths
28
Hospitalizations
How Dangerous Is Left ventricular dysfunction From PEGASPARGASE?
Of the 30 reports, 5 (16.7%) resulted in death, 28 (93.3%) required hospitalization, and 15 (50.0%) were considered life-threatening.
Is Left ventricular dysfunction Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 30 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Left ventricular dysfunction?
DOXORUBICIN (430)
CYCLOPHOSPHAMIDE (426)
TRASTUZUMAB (401)
CLOZAPINE (231)
SACUBITRIL\VALSARTAN (231)
BISOPROLOL (225)
PERTUZUMAB (207)
RITUXIMAB (202)
DOCETAXEL (199)
VINCRISTINE (193)
Which PEGASPARGASE Alternatives Have Lower Left ventricular dysfunction Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ