Does PEGASPARGASE Cause Mucormycosis? 61 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 61 reports of Mucormycosis have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.5% of all adverse event reports for PEGASPARGASE.
61
Reports of Mucormycosis with PEGASPARGASE
0.5%
of all PEGASPARGASE reports
20
Deaths
43
Hospitalizations
How Dangerous Is Mucormycosis From PEGASPARGASE?
Of the 61 reports, 20 (32.8%) resulted in death, 43 (70.5%) required hospitalization, and 28 (45.9%) were considered life-threatening.
Is Mucormycosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 61 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Mucormycosis?
TACROLIMUS (648)
MYCOPHENOLATE MOFETIL (468)
PREDNISONE (445)
DEXAMETHASONE (395)
METHYLPREDNISOLONE (387)
PREDNISOLONE (294)
CYCLOPHOSPHAMIDE (238)
AMPHOTERICIN B (232)
METHOTREXATE (231)
VORICONAZOLE (216)
Which PEGASPARGASE Alternatives Have Lower Mucormycosis Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ