Does PEGASPARGASE Cause Neutropenic sepsis? 19 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 19 reports of Neutropenic sepsis have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.2% of all adverse event reports for PEGASPARGASE.
19
Reports of Neutropenic sepsis with PEGASPARGASE
0.2%
of all PEGASPARGASE reports
12
Deaths
10
Hospitalizations
How Dangerous Is Neutropenic sepsis From PEGASPARGASE?
Of the 19 reports, 12 (63.2%) resulted in death, 10 (52.6%) required hospitalization, and 5 (26.3%) were considered life-threatening.
Is Neutropenic sepsis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 19 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Neutropenic sepsis?
CYCLOPHOSPHAMIDE (841)
CARBOPLATIN (757)
DEXAMETHASONE (684)
DOXORUBICIN (652)
RITUXIMAB (633)
VINCRISTINE (607)
ETOPOSIDE (569)
METHOTREXATE (411)
CISPLATIN (395)
DOCETAXEL (351)
Which PEGASPARGASE Alternatives Have Lower Neutropenic sepsis Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ