Does PEGASPARGASE Cause Pseudomonal sepsis? 211 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 211 reports of Pseudomonal sepsis have been filed in association with PEGASPARGASE (ONCASPAR). This represents 1.8% of all adverse event reports for PEGASPARGASE.
211
Reports of Pseudomonal sepsis with PEGASPARGASE
1.8%
of all PEGASPARGASE reports
152
Deaths
49
Hospitalizations
How Dangerous Is Pseudomonal sepsis From PEGASPARGASE?
Of the 211 reports, 152 (72.0%) resulted in death, 49 (23.2%) required hospitalization, and 24 (11.4%) were considered life-threatening.
Is Pseudomonal sepsis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 211 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Pseudomonal sepsis?
CYCLOPHOSPHAMIDE (307)
METHOTREXATE (303)
DEXAMETHASONE (258)
VINCRISTINE (258)
PREDNISONE (248)
CYTARABINE (231)
METHYLPREDNISOLONE (206)
ETOPOSIDE (198)
CYCLOSPORINE (197)
DAUNORUBICIN (186)
Which PEGASPARGASE Alternatives Have Lower Pseudomonal sepsis Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ