Does METHOTREXATE Cause Pseudomonal sepsis? 303 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 303 reports of Pseudomonal sepsis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
303
Reports of Pseudomonal sepsis with METHOTREXATE
0.1%
of all METHOTREXATE reports
180
Deaths
101
Hospitalizations
How Dangerous Is Pseudomonal sepsis From METHOTREXATE?
Of the 303 reports, 180 (59.4%) resulted in death, 101 (33.3%) required hospitalization, and 47 (15.5%) were considered life-threatening.
Is Pseudomonal sepsis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 303 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Pseudomonal sepsis?
CYCLOPHOSPHAMIDE (307)
DEXAMETHASONE (258)
VINCRISTINE (258)
PREDNISONE (248)
CYTARABINE (231)
PEGASPARGASE (211)
METHYLPREDNISOLONE (206)
ETOPOSIDE (198)
CYCLOSPORINE (197)
DAUNORUBICIN (186)
Which METHOTREXATE Alternatives Have Lower Pseudomonal sepsis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA