Does PEMETREXED Cause Acute hepatic failure? 22 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 22 reports of Acute hepatic failure have been filed in association with PEMETREXED (Pemetrexed). This represents 0.1% of all adverse event reports for PEMETREXED.
22
Reports of Acute hepatic failure with PEMETREXED
0.1%
of all PEMETREXED reports
15
Deaths
16
Hospitalizations
How Dangerous Is Acute hepatic failure From PEMETREXED?
Of the 22 reports, 15 (68.2%) resulted in death, 16 (72.7%) required hospitalization, and 5 (22.7%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMETREXED. However, 22 reports have been filed with the FAERS database.
What Other Side Effects Does PEMETREXED Cause?
Malignant neoplasm progression (2,149)
Off label use (1,663)
Anaemia (1,430)
Pancytopenia (1,236)
Neutropenia (1,200)
Nausea (1,195)
Diarrhoea (1,165)
Acute kidney injury (1,105)
Thrombocytopenia (1,059)
Disease progression (969)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which PEMETREXED Alternatives Have Lower Acute hepatic failure Risk?
PEMETREXED vs PEMIGATINIB
PEMETREXED vs PENICILLAMINE
PEMETREXED vs PENICILLIN
PEMETREXED vs PENICILLIN G
PEMETREXED vs PENICILLIN G BENZATHINE