Does PERTUZUMAB Cause Agranulocytosis? 80 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 80 reports of Agranulocytosis have been filed in association with PERTUZUMAB (PERJETA). This represents 0.4% of all adverse event reports for PERTUZUMAB.
80
Reports of Agranulocytosis with PERTUZUMAB
0.4%
of all PERTUZUMAB reports
2
Deaths
50
Hospitalizations
How Dangerous Is Agranulocytosis From PERTUZUMAB?
Of the 80 reports, 2 (2.5%) resulted in death, 50 (62.5%) required hospitalization, and 18 (22.5%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PERTUZUMAB. However, 80 reports have been filed with the FAERS database.
What Other Side Effects Does PERTUZUMAB Cause?
Diarrhoea (3,343)
Off label use (1,886)
Fatigue (1,672)
Nausea (1,669)
Myelosuppression (1,311)
Disease progression (1,142)
Vomiting (1,096)
Dyspnoea (987)
Neuropathy peripheral (983)
Pyrexia (926)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which PERTUZUMAB Alternatives Have Lower Agranulocytosis Risk?
PERTUZUMAB vs PERTUZUMAB\TRASTUZUMAB
PERTUZUMAB vs PETROLATUM
PERTUZUMAB vs PEVONEDISTAT
PERTUZUMAB vs PEXIDARTINIB
PERTUZUMAB vs PHENACETIN