Does PERTUZUMAB Cause Cardiotoxicity? 260 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 260 reports of Cardiotoxicity have been filed in association with PERTUZUMAB (PERJETA). This represents 1.2% of all adverse event reports for PERTUZUMAB.
260
Reports of Cardiotoxicity with PERTUZUMAB
1.2%
of all PERTUZUMAB reports
10
Deaths
33
Hospitalizations
How Dangerous Is Cardiotoxicity From PERTUZUMAB?
Of the 260 reports, 10 (3.8%) resulted in death, 33 (12.7%) required hospitalization, and 12 (4.6%) were considered life-threatening.
Is Cardiotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PERTUZUMAB. However, 260 reports have been filed with the FAERS database.
What Other Side Effects Does PERTUZUMAB Cause?
Diarrhoea (3,343)
Off label use (1,886)
Fatigue (1,672)
Nausea (1,669)
Myelosuppression (1,311)
Disease progression (1,142)
Vomiting (1,096)
Dyspnoea (987)
Neuropathy peripheral (983)
Pyrexia (926)
What Other Drugs Cause Cardiotoxicity?
DOXORUBICIN (1,366)
CYCLOPHOSPHAMIDE (1,009)
TRASTUZUMAB (950)
VINCRISTINE (446)
FLUOROURACIL (425)
RITUXIMAB (389)
ETOPOSIDE (366)
CAPECITABINE (307)
TOCILIZUMAB (278)
PREDNISONE (277)
Which PERTUZUMAB Alternatives Have Lower Cardiotoxicity Risk?
PERTUZUMAB vs PERTUZUMAB\TRASTUZUMAB
PERTUZUMAB vs PETROLATUM
PERTUZUMAB vs PEVONEDISTAT
PERTUZUMAB vs PEXIDARTINIB
PERTUZUMAB vs PHENACETIN