Does PIPERACILLIN Cause Hepatic cytolysis? 32 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 32 reports of Hepatic cytolysis have been filed in association with PIPERACILLIN (Piperacillin and Tazobactam). This represents 3.1% of all adverse event reports for PIPERACILLIN.
32
Reports of Hepatic cytolysis with PIPERACILLIN
3.1%
of all PIPERACILLIN reports
5
Deaths
19
Hospitalizations
How Dangerous Is Hepatic cytolysis From PIPERACILLIN?
Of the 32 reports, 5 (15.6%) resulted in death, 19 (59.4%) required hospitalization, and 5 (15.6%) were considered life-threatening.
Is Hepatic cytolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PIPERACILLIN. However, 32 reports have been filed with the FAERS database.
What Other Side Effects Does PIPERACILLIN Cause?
Pyrexia (83)
Drug reaction with eosinophilia and systemic symptoms (77)
Drug ineffective (73)
Off label use (68)
Eosinophilia (60)
Acute kidney injury (56)
Rash (55)
Rash maculo-papular (52)
Toxic epidermal necrolysis (45)
Dyspnoea (43)
What Other Drugs Cause Hepatic cytolysis?
ACETAMINOPHEN (1,469)
ATORVASTATIN (681)
PEMBROLIZUMAB (601)
CARBOPLATIN (577)
METHOTREXATE (468)
SULFAMETHOXAZOLE\TRIMETHOPRIM (356)
PACLITAXEL (324)
ENOXAPARIN (307)
AMOXICILLIN (273)
VALACYCLOVIR (261)
Which PIPERACILLIN Alternatives Have Lower Hepatic cytolysis Risk?
PIPERACILLIN vs PIPERACILLIN\TAZOBACTAM
PIPERACILLIN vs PIRACETAM
PIPERACILLIN vs PIRARUBICIN
PIPERACILLIN vs PIRFENIDONE
PIPERACILLIN vs PIRIBEDIL