Does PIPERACILLIN\TAZOBACTAM Cause Hypertransaminasaemia? 76 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 76 reports of Hypertransaminasaemia have been filed in association with PIPERACILLIN\TAZOBACTAM. This represents 0.4% of all adverse event reports for PIPERACILLIN\TAZOBACTAM.
76
Reports of Hypertransaminasaemia with PIPERACILLIN\TAZOBACTAM
0.4%
of all PIPERACILLIN\TAZOBACTAM reports
20
Deaths
32
Hospitalizations
How Dangerous Is Hypertransaminasaemia From PIPERACILLIN\TAZOBACTAM?
Of the 76 reports, 20 (26.3%) resulted in death, 32 (42.1%) required hospitalization, and 15 (19.7%) were considered life-threatening.
Is Hypertransaminasaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PIPERACILLIN\TAZOBACTAM. However, 76 reports have been filed with the FAERS database.
What Other Side Effects Does PIPERACILLIN\TAZOBACTAM Cause?
Drug ineffective (2,273)
Off label use (1,586)
Acute kidney injury (1,539)
Drug reaction with eosinophilia and systemic symptoms (1,157)
Pyrexia (1,113)
Rash (962)
Condition aggravated (928)
Thrombocytopenia (694)
Diarrhoea (671)
Rash maculo-papular (629)
What Other Drugs Cause Hypertransaminasaemia?
METHOTREXATE (436)
ACETAMINOPHEN (326)
PACLITAXEL (318)
CARBOPLATIN (304)
PEMBROLIZUMAB (231)
ATORVASTATIN (207)
CYCLOPHOSPHAMIDE (202)
PREDNISONE (198)
GEMCITABINE (196)
DEXAMETHASONE (169)
Which PIPERACILLIN\TAZOBACTAM Alternatives Have Lower Hypertransaminasaemia Risk?
PIPERACILLIN\TAZOBACTAM vs PIRACETAM
PIPERACILLIN\TAZOBACTAM vs PIRARUBICIN
PIPERACILLIN\TAZOBACTAM vs PIRFENIDONE
PIPERACILLIN\TAZOBACTAM vs PIRIBEDIL
PIPERACILLIN\TAZOBACTAM vs PIRITRAMIDE