Does RUXOLITINIB Cause Cholangitis? 13 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 13 reports of Cholangitis have been filed in association with RUXOLITINIB (OPZELURA). This represents 0.0% of all adverse event reports for RUXOLITINIB.
13
Reports of Cholangitis with RUXOLITINIB
0.0%
of all RUXOLITINIB reports
3
Deaths
10
Hospitalizations
How Dangerous Is Cholangitis From RUXOLITINIB?
Of the 13 reports, 3 (23.1%) resulted in death, 10 (76.9%) required hospitalization, and 1 (7.7%) were considered life-threatening.
Is Cholangitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RUXOLITINIB. However, 13 reports have been filed with the FAERS database.
What Other Side Effects Does RUXOLITINIB Cause?
Off label use (12,492)
Death (6,561)
Fatigue (5,663)
Anaemia (3,593)
Haemoglobin decreased (3,297)
Platelet count decreased (3,028)
Diarrhoea (2,531)
Asthenia (2,529)
Dizziness (2,398)
Pneumonia (2,343)
What Other Drugs Cause Cholangitis?
NIVOLUMAB (389)
PEMBROLIZUMAB (357)
PACLITAXEL (289)
GEMCITABINE (225)
TACROLIMUS (213)
BEVACIZUMAB (176)
FLUOROURACIL (175)
DURVALUMAB (157)
OXALIPLATIN (147)
IRINOTECAN (146)
Which RUXOLITINIB Alternatives Have Lower Cholangitis Risk?
RUXOLITINIB vs SABRIL
RUXOLITINIB vs SACCHAROMYCES CEREVISIAE
RUXOLITINIB vs SACITUZUMAB GOVITECAN
RUXOLITINIB vs SACITUZUMAB GOVITECAN-HZIY
RUXOLITINIB vs SACROSIDASE