Does SARILUMAB Cause Agranulocytosis? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Agranulocytosis have been filed in association with SARILUMAB (KEVZARA). This represents 0.1% of all adverse event reports for SARILUMAB.
15
Reports of Agranulocytosis with SARILUMAB
0.1%
of all SARILUMAB reports
1
Deaths
12
Hospitalizations
How Dangerous Is Agranulocytosis From SARILUMAB?
Of the 15 reports, 1 (6.7%) resulted in death, 12 (80.0%) required hospitalization, and 3 (20.0%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SARILUMAB. However, 15 reports have been filed with the FAERS database.
What Other Side Effects Does SARILUMAB Cause?
Drug ineffective (5,065)
Pain (4,833)
Arthralgia (4,139)
Rheumatoid arthritis (3,963)
Joint swelling (3,951)
Condition aggravated (3,247)
Fatigue (3,000)
Rash (2,912)
Alopecia (2,660)
Abdominal discomfort (2,600)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which SARILUMAB Alternatives Have Lower Agranulocytosis Risk?
SARILUMAB vs SATRALIZUMAB
SARILUMAB vs SATRALIZUMAB-MWGE
SARILUMAB vs SAXAGLIPTIN
SARILUMAB vs SCHOLL'S INGROWN TOENAIL PAIN RELIEVER
SARILUMAB vs SCOPOLAMINE