Does SORAFENIB Cause Cholangitis? 16 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 16 reports of Cholangitis have been filed in association with SORAFENIB (sorafenib). This represents 0.2% of all adverse event reports for SORAFENIB.
16
Reports of Cholangitis with SORAFENIB
0.2%
of all SORAFENIB reports
3
Deaths
4
Hospitalizations
How Dangerous Is Cholangitis From SORAFENIB?
Of the 16 reports, 3 (18.8%) resulted in death, 4 (25.0%) required hospitalization.
Is Cholangitis Listed in the Official Label?
Yes, Cholangitis is listed as a known adverse reaction in the official FDA drug label for SORAFENIB.
What Other Side Effects Does SORAFENIB Cause?
Hepatocellular carcinoma (1,665)
Diarrhoea (1,611)
Off label use (1,587)
Fatigue (1,041)
Palmar-plantar erythrodysaesthesia syndrome (1,040)
Decreased appetite (906)
Death (904)
Asthenia (777)
Nausea (716)
Rash (613)
What Other Drugs Cause Cholangitis?
NIVOLUMAB (389)
PEMBROLIZUMAB (357)
PACLITAXEL (289)
GEMCITABINE (225)
TACROLIMUS (213)
BEVACIZUMAB (176)
FLUOROURACIL (175)
DURVALUMAB (157)
OXALIPLATIN (147)
IRINOTECAN (146)
Which SORAFENIB Alternatives Have Lower Cholangitis Risk?
SORAFENIB vs SORGHUM HALEPENSE POLLEN
SORAFENIB vs SOTAGLIFLOZIN
SORAFENIB vs SOTALOL
SORAFENIB vs SOTATERCEPT
SORAFENIB vs SOTATERCEPT-CSRK