Does SPIRONOLACTONE Cause Agranulocytosis? 96 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 96 reports of Agranulocytosis have been filed in association with SPIRONOLACTONE (spironolactone). This represents 0.5% of all adverse event reports for SPIRONOLACTONE.
96
Reports of Agranulocytosis with SPIRONOLACTONE
0.5%
of all SPIRONOLACTONE reports
6
Deaths
69
Hospitalizations
How Dangerous Is Agranulocytosis From SPIRONOLACTONE?
Of the 96 reports, 6 (6.3%) resulted in death, 69 (71.9%) required hospitalization, and 34 (35.4%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for SPIRONOLACTONE.
What Other Side Effects Does SPIRONOLACTONE Cause?
Acute kidney injury (3,273)
Hyperkalaemia (2,518)
Hypotension (1,583)
Dyspnoea (1,468)
Drug ineffective (1,379)
Hyponatraemia (1,166)
Dizziness (991)
Fatigue (990)
Fall (947)
Off label use (899)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which SPIRONOLACTONE Alternatives Have Lower Agranulocytosis Risk?
SPIRONOLACTONE vs SPRYCEL
SPIRONOLACTONE vs STALEVO
SPIRONOLACTONE vs STANNOUS FLUORIDE
SPIRONOLACTONE vs STANOZOLOL
SPIRONOLACTONE vs STAVUDINE