Does TACROLIMUS Cause Agranulocytosis? 165 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 165 reports of Agranulocytosis have been filed in association with TACROLIMUS (Tacrolimus). This represents 0.2% of all adverse event reports for TACROLIMUS.
165
Reports of Agranulocytosis with TACROLIMUS
0.2%
of all TACROLIMUS reports
21
Deaths
108
Hospitalizations
How Dangerous Is Agranulocytosis From TACROLIMUS?
Of the 165 reports, 21 (12.7%) resulted in death, 108 (65.5%) required hospitalization, and 31 (18.8%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for TACROLIMUS.
What Other Side Effects Does TACROLIMUS Cause?
Off label use (8,718)
Drug ineffective (6,214)
Product use in unapproved indication (5,057)
Acute kidney injury (4,005)
Transplant rejection (3,526)
Cytomegalovirus infection (3,320)
Covid-19 (3,201)
Drug interaction (2,896)
Diarrhoea (2,854)
Toxicity to various agents (2,845)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which TACROLIMUS Alternatives Have Lower Agranulocytosis Risk?
TACROLIMUS vs TACROLIMUS\TACROLIMUS ANHYDROUS
TACROLIMUS vs TADALAFIL
TACROLIMUS vs TAFAMIDIS
TACROLIMUS vs TAFAMIDIS MEGLUMINE
TACROLIMUS vs TAFASITAMAB