Does TEMOZOLOMIDE Cause Agranulocytosis? 77 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 77 reports of Agranulocytosis have been filed in association with TEMOZOLOMIDE (TEMOZOLOMIDE). This represents 0.5% of all adverse event reports for TEMOZOLOMIDE.
77
Reports of Agranulocytosis with TEMOZOLOMIDE
0.5%
of all TEMOZOLOMIDE reports
22
Deaths
62
Hospitalizations
How Dangerous Is Agranulocytosis From TEMOZOLOMIDE?
Of the 77 reports, 22 (28.6%) resulted in death, 62 (80.5%) required hospitalization, and 21 (27.3%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TEMOZOLOMIDE. However, 77 reports have been filed with the FAERS database.
What Other Side Effects Does TEMOZOLOMIDE Cause?
Disease progression (1,562)
Death (1,403)
Off label use (1,357)
Product use in unapproved indication (1,353)
Thrombocytopenia (1,300)
Drug ineffective (1,131)
Nausea (1,071)
Neutropenia (809)
Malignant neoplasm progression (779)
Fatigue (766)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which TEMOZOLOMIDE Alternatives Have Lower Agranulocytosis Risk?
TEMOZOLOMIDE vs TEMSIROLIMUS
TEMOZOLOMIDE vs TENAMFETAMINE
TEMOZOLOMIDE vs TENAPANOR
TEMOZOLOMIDE vs TENECTEPLASE
TEMOZOLOMIDE vs TENELIGLIPTIN