Does TRAMETINIB DIMETHYL SULFOXIDE Cause Cholangitis? 18 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 18 reports of Cholangitis have been filed in association with TRAMETINIB DIMETHYL SULFOXIDE (Mekinist). This represents 0.1% of all adverse event reports for TRAMETINIB DIMETHYL SULFOXIDE.
18
Reports of Cholangitis with TRAMETINIB DIMETHYL SULFOXIDE
0.1%
of all TRAMETINIB DIMETHYL SULFOXIDE reports
0
Deaths
7
Hospitalizations
How Dangerous Is Cholangitis From TRAMETINIB DIMETHYL SULFOXIDE?
Of the 18 reports, 7 (38.9%) required hospitalization.
Is Cholangitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRAMETINIB DIMETHYL SULFOXIDE. However, 18 reports have been filed with the FAERS database.
What Other Side Effects Does TRAMETINIB DIMETHYL SULFOXIDE Cause?
Death (2,998)
Pyrexia (2,660)
Rash (1,271)
Fatigue (1,143)
Malignant neoplasm progression (1,114)
Nausea (1,085)
Chills (965)
Diarrhoea (867)
Vomiting (720)
Product use in unapproved indication (687)
What Other Drugs Cause Cholangitis?
NIVOLUMAB (389)
PEMBROLIZUMAB (357)
PACLITAXEL (289)
GEMCITABINE (225)
TACROLIMUS (213)
BEVACIZUMAB (176)
FLUOROURACIL (175)
DURVALUMAB (157)
OXALIPLATIN (147)
IRINOTECAN (146)
Which TRAMETINIB DIMETHYL SULFOXIDE Alternatives Have Lower Cholangitis Risk?
TRAMETINIB DIMETHYL SULFOXIDE vs TRANDOLAPRIL
TRAMETINIB DIMETHYL SULFOXIDE vs TRANDOLAPRIL\VERAPAMIL
TRAMETINIB DIMETHYL SULFOXIDE vs TRANEXAMIC ACID
TRAMETINIB DIMETHYL SULFOXIDE vs TRANYLCYPROMINE
TRAMETINIB DIMETHYL SULFOXIDE vs TRASTUZUMAB