Does TRASTUZUMAB Cause Agranulocytosis? 163 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 163 reports of Agranulocytosis have been filed in association with TRASTUZUMAB (Trazimera). This represents 0.4% of all adverse event reports for TRASTUZUMAB.
163
Reports of Agranulocytosis with TRASTUZUMAB
0.4%
of all TRASTUZUMAB reports
11
Deaths
98
Hospitalizations
How Dangerous Is Agranulocytosis From TRASTUZUMAB?
Of the 163 reports, 11 (6.7%) resulted in death, 98 (60.1%) required hospitalization, and 29 (17.8%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRASTUZUMAB. However, 163 reports have been filed with the FAERS database.
What Other Side Effects Does TRASTUZUMAB Cause?
Diarrhoea (4,996)
Off label use (3,802)
Nausea (3,499)
Fatigue (3,417)
Myelosuppression (2,552)
Disease progression (2,449)
Death (2,378)
Vomiting (2,244)
Dyspnoea (2,010)
Pyrexia (1,886)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which TRASTUZUMAB Alternatives Have Lower Agranulocytosis Risk?
TRASTUZUMAB vs TRASTUZUMAB-ANNS
TRASTUZUMAB vs TRASTUZUMAB DERUXTECAN
TRASTUZUMAB vs TRASTUZUMAB-DKST
TRASTUZUMAB vs TRASTUZUMAB-DTTB
TRASTUZUMAB vs TRASTUZUMAB EMTANSINE