Does VALPROATE Cause Agranulocytosis? 79 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 79 reports of Agranulocytosis have been filed in association with VALPROATE (Valproate Sodium). This represents 0.5% of all adverse event reports for VALPROATE.
79
Reports of Agranulocytosis with VALPROATE
0.5%
of all VALPROATE reports
2
Deaths
38
Hospitalizations
How Dangerous Is Agranulocytosis From VALPROATE?
Of the 79 reports, 2 (2.5%) resulted in death, 38 (48.1%) required hospitalization, and 29 (36.7%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for VALPROATE.
What Other Side Effects Does VALPROATE Cause?
Foetal exposure during pregnancy (1,982)
Drug ineffective (1,268)
Seizure (1,083)
Epilepsy (878)
Somnolence (843)
Off label use (744)
Drug abuse (705)
Sopor (577)
Dysmorphism (552)
Drug interaction (513)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which VALPROATE Alternatives Have Lower Agranulocytosis Risk?
VALPROATE vs VALPROIC ACID
VALPROATE vs VALPROMIDE
VALPROATE vs VALSARTAN
VALPROATE vs VALTREX
VALPROATE vs VAMOROLONE