Does VALPROIC ACID Cause Agranulocytosis? 56 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 56 reports of Agranulocytosis have been filed in association with VALPROIC ACID (Valproic Acid). This represents 0.3% of all adverse event reports for VALPROIC ACID.
56
Reports of Agranulocytosis with VALPROIC ACID
0.3%
of all VALPROIC ACID reports
0
Deaths
30
Hospitalizations
How Dangerous Is Agranulocytosis From VALPROIC ACID?
Of the 56 reports, 30 (53.6%) required hospitalization, and 10 (17.9%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for VALPROIC ACID.
What Other Side Effects Does VALPROIC ACID Cause?
Drug ineffective (3,511)
Drug interaction (1,542)
Toxicity to various agents (1,517)
Off label use (1,503)
Seizure (1,335)
Foetal exposure during pregnancy (1,046)
Somnolence (831)
Completed suicide (723)
Overdose (691)
Condition aggravated (673)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which VALPROIC ACID Alternatives Have Lower Agranulocytosis Risk?
VALPROIC ACID vs VALPROMIDE
VALPROIC ACID vs VALSARTAN
VALPROIC ACID vs VALTREX
VALPROIC ACID vs VAMOROLONE
VALPROIC ACID vs VANCOMYCIN