Does VEMURAFENIB Cause Agranulocytosis? 19 Reports in FDA Database

Q: Does VEMURAFENIB cause Agranulocytosis?

19 reports of Agranulocytosis have been filed with the FDA for VEMURAFENIB, representing 0.2% of all VEMURAFENIB adverse event reports.

Q: How dangerous is Agranulocytosis from VEMURAFENIB?

Of 19 reports, 2 (10.5%) resulted in death and 12 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 19 reports of Agranulocytosis have been filed in association with VEMURAFENIB (ZELBORAF). This represents 0.2% of all adverse event reports for VEMURAFENIB.

Reports of Agranulocytosis with VEMURAFENIB

0.2%

of all VEMURAFENIB reports

Deaths

Hospitalizations

How Dangerous Is Agranulocytosis From VEMURAFENIB?

Of the 19 reports, 2 (10.5%) resulted in death, 12 (63.2%) required hospitalization, and 1 (5.3%) were considered life-threatening.

Is Agranulocytosis Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for VEMURAFENIB. However, 19 reports have been filed with the FAERS database.

What Other Side Effects Does VEMURAFENIB Cause?

Rash (1,202) Arthralgia (783) Off label use (782) Fatigue (773) Diarrhoea (655) Nausea (601) Pyrexia (569) Death (505) Alopecia (445) Decreased appetite (383)

What Other Drugs Cause Agranulocytosis?

CLOZAPINE (1,766) CYCLOPHOSPHAMIDE (1,242) RITUXIMAB (1,154) SULFAMETHOXAZOLE\TRIMETHOPRIM (797) PANTOPRAZOLE (599) METHOTREXATE (550) SODIUM (549) EPIRUBICIN (491) METAMIZOLE (438) DOCETAXEL (436)

Which VEMURAFENIB Alternatives Have Lower Agranulocytosis Risk?

VEMURAFENIB vs VENETOCLAX VEMURAFENIB vs VENLAFAXINE VEMURAFENIB vs VENTAVIS VEMURAFENIB vs VENTOLIN VEMURAFENIB vs VENTOLIN HFA

VEMURAFENIB Full Profile All Agranulocytosis Reports All Drugs Causing Agranulocytosis VEMURAFENIB Demographics