Does VINCRISTINE Cause Agranulocytosis? 344 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 344 reports of Agranulocytosis have been filed in association with VINCRISTINE (VinCRIStine Sulfate). This represents 0.5% of all adverse event reports for VINCRISTINE.
344
Reports of Agranulocytosis with VINCRISTINE
0.5%
of all VINCRISTINE reports
42
Deaths
205
Hospitalizations
How Dangerous Is Agranulocytosis From VINCRISTINE?
Of the 344 reports, 42 (12.2%) resulted in death, 205 (59.6%) required hospitalization, and 118 (34.3%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VINCRISTINE. However, 344 reports have been filed with the FAERS database.
What Other Side Effects Does VINCRISTINE Cause?
Febrile neutropenia (8,676)
Off label use (6,562)
Disease progression (5,252)
Neutropenia (4,982)
Drug ineffective (4,084)
Pyrexia (3,460)
Product use in unapproved indication (3,073)
Thrombocytopenia (2,940)
Sepsis (2,791)
Anaemia (2,603)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which VINCRISTINE Alternatives Have Lower Agranulocytosis Risk?
VINCRISTINE vs VINDESINE
VINCRISTINE vs VINORELBINE
VINCRISTINE vs VINORELBINE\VINORELBINE
VINCRISTINE vs VIREAD
VINCRISTINE vs VISIPAQUE