Acanthamoeba infection: Which Medications Cause It? (126 Reports Across 35 Drugs)
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Acanthamoeba infection has been reported as an adverse event with 35 different drugs in the FDA's FAERS database, with 126 total reports. 62 of these reports resulted in death.The drugs most commonly associated with Acanthamoeba infection are PREDNISONE, TACROLIMUS, and MYCOPHENOLATE MOFETIL.
126
Total Reports
35
Drugs Involved
62
Deaths
80
Hospitalizations
52.0 yrs
Average Patient Age
32.7% / 67.3%
Female / Male
Which Drugs Cause Acanthamoeba infection Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| PREDNISONE | 64 | 0.0% | 38 | 46 | 13 |
| TACROLIMUS | 62 | 0.1% | 41 | 46 | 15 |
| MYCOPHENOLATE MOFETIL | 29 | 0.0% | 15 | 20 | 4 |
| MYCOPHENOLIC ACID | 25 | 0.2% | 15 | 21 | 6 |
| PREDNISOLONE | 23 | 0.0% | 4 | 19 | 8 |
| CYCLOSPORINE | 16 | 0.0% | 1 | 15 | 6 |
| CYCLOPHOSPHAMIDE | 14 | 0.0% | 2 | 11 | 6 |
| ALEMTUZUMAB | 13 | 0.1% | 5 | 10 | 7 |
| ETOPOSIDE | 12 | 0.0% | 1 | 10 | 5 |
| RITUXIMAB | 12 | 0.0% | 9 | 5 | 2 |
| MELPHALAN | 10 | 0.1% | 3 | 9 | 7 |
| DOXORUBICIN | 9 | 0.0% | 1 | 7 | 5 |
| INFLIXIMAB | 9 | 0.0% | 3 | 5 | 2 |
| METHOTREXATE | 9 | 0.0% | 2 | 9 | 0 |
| MILTEFOSINE | 9 | 3.7% | 5 | 6 | 1 |
| VINCRISTINE | 9 | 0.0% | 1 | 7 | 5 |
| BLEOMYCIN | 8 | 0.1% | 0 | 7 | 5 |
| BRENTUXIMAB VEDOTIN | 8 | 0.1% | 0 | 7 | 5 |
| CARBOPLATIN | 8 | 0.0% | 0 | 7 | 5 |
| CARMUSTINE | 8 | 0.2% | 0 | 7 | 5 |