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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Accidental overdose: Which Medications Cause It? (26,093 Reports Across 768 Drugs)

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Accidental overdose has been reported as an adverse event with 768 different drugs in the FDA's FAERS database, with 26,093 total reports. 4,908 of these reports resulted in death.The drugs most commonly associated with Accidental overdose are OXYCODONE, DULAGLUTIDE, and TIRZEPATIDE.

26,093
Total Reports
768
Drugs Involved
4,908
Deaths
6,922
Hospitalizations
48.0 yrs
Average Patient Age
55.0% / 45.0%
Female / Male

Which Drugs Cause Accidental overdose Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
OXYCODONE 1,861 1.0% 1,392 285 84
DULAGLUTIDE 1,814 2.5% 0 19 0
TIRZEPATIDE 1,600 1.6% 0 9 0
FENTANYL 1,577 1.7% 1,287 196 67
MORPHINE 1,343 1.1% 1,101 188 126
ACETAMINOPHEN 1,245 0.9% 249 700 146
HYDROMORPHONE 945 1.1% 801 134 37
ACETAMINOPHEN\HYDROCODONE 899 0.8% 762 117 21
BUPRENORPHINE 898 1.1% 788 95 18
ACETAMINOPHEN\OXYCODONE 879 0.9% 769 79 11
HYDROCODONE 812 1.7% 779 44 14
TAPENTADOL 693 2.4% 673 16 0
CETIRIZINE 678 1.4% 24 44 22
OXYMORPHONE 656 1.7% 642 13 2
METHOTREXATE 631 0.3% 171 425 134
ASPIRIN\OXYCODONE 616 2.4% 613 10 0
CITALOPRAM 543 13.0% 532 3 6
TRAMADOL 516 0.7% 239 212 54
DEXTROMETHORPHAN HYDROBROMIDE\GUAIFENESIN 515 7.6% 2 6 0
METFORMIN 515 0.6% 53 304 128

View all 768 drugs →

Top 3 Drugs Associated With Accidental overdose

1,861 reports
1,814 reports
1,600 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)