Activated partial thromboplastin time prolonged: Which Medications Cause It? (2,265 Reports Across 395 Drugs)
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Activated partial thromboplastin time prolonged has been reported as an adverse event with 395 different drugs in the FDA's FAERS database, with 2,265 total reports. 412 of these reports resulted in death.The drugs most commonly associated with Activated partial thromboplastin time prolonged are DABIGATRAN ETEXILATE, HEPARIN, and RIVAROXABAN.
2,265
Total Reports
395
Drugs Involved
412
Deaths
1,342
Hospitalizations
59.9 yrs
Average Patient Age
43.3% / 56.7%
Female / Male
Which Drugs Cause Activated partial thromboplastin time prolonged Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| DABIGATRAN ETEXILATE | 264 | 0.7% | 45 | 182 | 40 |
| HEPARIN | 225 | 1.2% | 103 | 137 | 87 |
| RIVAROXABAN | 163 | 0.1% | 5 | 78 | 21 |
| WARFARIN | 146 | 0.4% | 65 | 121 | 58 |
| ACETAMINOPHEN | 119 | 0.1% | 76 | 109 | 86 |
| ALLOPURINOL | 110 | 0.6% | 76 | 102 | 70 |
| AMIODARONE | 99 | 0.4% | 69 | 91 | 69 |
| METRONIDAZOLE | 98 | 0.4% | 87 | 90 | 80 |
| SIMVASTATIN | 94 | 0.4% | 72 | 87 | 69 |
| DARBEPOETIN ALFA | 93 | 0.3% | 60 | 88 | 55 |
| ASPIRIN | 87 | 0.1% | 8 | 49 | 12 |
| APIXABAN | 86 | 0.1% | 4 | 41 | 10 |
| CEFTRIAXONE | 83 | 0.4% | 73 | 74 | 65 |
| PHYTONADIONE | 82 | 6.5% | 81 | 78 | 75 |
| ALBUTEROL | 81 | 0.1% | 80 | 77 | 76 |
| LANSOPRAZOLE | 81 | 0.1% | 76 | 77 | 73 |
| POTASSIUM | 78 | 0.7% | 67 | 75 | 64 |
| GABAPENTIN | 77 | 0.1% | 71 | 72 | 66 |
| ONDANSETRON | 77 | 0.3% | 76 | 73 | 73 |
| DALTEPARIN | 76 | 2.1% | 62 | 64 | 60 |