Acute chest syndrome: Which Medications Cause It? (650 Reports Across 29 Drugs)
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Acute chest syndrome has been reported as an adverse event with 29 different drugs in the FDA's FAERS database, with 650 total reports. 28 of these reports resulted in death.The drugs most commonly associated with Acute chest syndrome are VOXELOTOR, GLUTAMINE, and CRIZANLIZUMAB-TMCA.
650
Total Reports
29
Drugs Involved
28
Deaths
480
Hospitalizations
25.4 yrs
Average Patient Age
52.3% / 47.7%
Female / Male
Which Drugs Cause Acute chest syndrome Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| VOXELOTOR | 372 | 1.7% | 7 | 266 | 16 |
| GLUTAMINE | 46 | 1.4% | 1 | 37 | 2 |
| CRIZANLIZUMAB-TMCA | 37 | 3.3% | 2 | 30 | 3 |
| HYDROXYUREA | 25 | 0.4% | 2 | 23 | 0 |
| MORPHINE | 23 | 0.0% | 0 | 19 | 16 |
| METHYLPREDNISOLONE | 18 | 0.0% | 0 | 14 | 0 |
| DEFERASIROX | 16 | 0.1% | 3 | 12 | 3 |
| PREDNISONE | 14 | 0.0% | 2 | 8 | 5 |
| RITUXIMAB | 14 | 0.0% | 0 | 13 | 0 |
| HYDROMORPHONE | 13 | 0.0% | 0 | 13 | 4 |
| FENTANYL | 10 | 0.0% | 0 | 5 | 9 |
| HUMAN IMMUNOGLOBULIN G | 10 | 0.0% | 0 | 10 | 0 |
| INFLIXIMAB | 10 | 0.0% | 0 | 10 | 0 |
| ERYTHROPOIETIN | 9 | 0.1% | 0 | 8 | 0 |
| CODEINE | 8 | 0.0% | 2 | 6 | 3 |
| DEFERIPRONE | 8 | 0.3% | 2 | 6 | 1 |
| ACETAZOLAMIDE | 7 | 0.3% | 0 | 7 | 2 |
| CRIZANLIZUMAB | 7 | 5.6% | 0 | 6 | 3 |
| IRON | 7 | 0.3% | 0 | 7 | 0 |
| OXYCODONE | 7 | 0.0% | 0 | 7 | 1 |