Adrenal suppression: Which Medications Cause It? (566 Reports Across 69 Drugs)
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Adrenal suppression has been reported as an adverse event with 69 different drugs in the FDA's FAERS database, with 566 total reports. 8 of these reports resulted in death.The drugs most commonly associated with Adrenal suppression are HYDROCORTISONE, FLUTICASONE, and PREDNISONE.
566
Total Reports
69
Drugs Involved
8
Deaths
139
Hospitalizations
30.9 yrs
Average Patient Age
49.7% / 50.3%
Female / Male
Which Drugs Cause Adrenal suppression Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| HYDROCORTISONE | 115 | 0.5% | 0 | 51 | 5 |
| FLUTICASONE | 94 | 0.3% | 0 | 7 | 0 |
| PREDNISONE | 92 | 0.1% | 2 | 22 | 9 |
| FLUTICASONE\SALMETEROL | 82 | 0.2% | 2 | 50 | 1 |
| PREDNISOLONE | 68 | 0.1% | 1 | 11 | 3 |
| BUDESONIDE\FORMOTEROL | 56 | 0.2% | 0 | 41 | 0 |
| CYCLOSPORINE | 51 | 0.1% | 0 | 0 | 0 |
| METHOTREXATE | 51 | 0.0% | 0 | 1 | 0 |
| LANSOPRAZOLE | 49 | 0.1% | 0 | 45 | 0 |
| CELECOXIB | 48 | 0.2% | 0 | 0 | 0 |
| BUDESONIDE | 45 | 0.2% | 2 | 8 | 0 |
| CICLESONIDE | 45 | 0.8% | 0 | 45 | 0 |
| TOCILIZUMAB | 45 | 0.1% | 0 | 0 | 0 |
| ETANERCEPT | 43 | 0.0% | 0 | 1 | 0 |
| INFLIXIMAB | 43 | 0.0% | 0 | 1 | 0 |
| ANAKINRA | 42 | 0.4% | 0 | 0 | 0 |
| ASPIRIN | 42 | 0.1% | 0 | 0 | 0 |
| TINZAPARIN | 42 | 2.4% | 0 | 0 | 0 |
| HUMAN IMMUNOGLOBULIN G | 40 | 0.1% | 0 | 1 | 0 |
| MAGNESIUM | 36 | 0.4% | 0 | 36 | 0 |