Amyotrophic lateral sclerosis: Which Medications Cause It? (1,370 Reports Across 75 Drugs)
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Amyotrophic lateral sclerosis has been reported as an adverse event with 75 different drugs in the FDA's FAERS database, with 1,370 total reports. 452 of these reports resulted in death.The drugs most commonly associated with Amyotrophic lateral sclerosis are EDARAVONE, ADALIMUMAB, and ETANERCEPT.
1,370
Total Reports
75
Drugs Involved
452
Deaths
257
Hospitalizations
63.2 yrs
Average Patient Age
47.7% / 52.3%
Female / Male
Which Drugs Cause Amyotrophic lateral sclerosis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| EDARAVONE | 199 | 5.3% | 173 | 13 | 0 |
| ADALIMUMAB | 121 | 0.0% | 11 | 18 | 3 |
| ETANERCEPT | 78 | 0.0% | 9 | 10 | 4 |
| INFLIXIMAB | 64 | 0.1% | 8 | 8 | 3 |
| METHOTREXATE | 57 | 0.0% | 5 | 12 | 0 |
| DEXTROMETHORPHAN HYDROBROMIDE\QUINIDINE | 48 | 0.9% | 29 | 2 | 0 |
| RITUXIMAB | 41 | 0.0% | 5 | 8 | 1 |
| ABATACEPT | 38 | 0.0% | 1 | 8 | 4 |
| TOFERSEN | 38 | 10.4% | 21 | 13 | 0 |
| TOCILIZUMAB | 36 | 0.0% | 1 | 4 | 0 |
| TOFACITINIB | 34 | 0.0% | 3 | 5 | 0 |
| LEFLUNOMIDE | 33 | 0.1% | 1 | 0 | 0 |
| ATORVASTATIN | 31 | 0.0% | 5 | 5 | 3 |
| HYDROXYCHLOROQUINE | 27 | 0.0% | 0 | 5 | 0 |
| RILUZOLE | 27 | 1.9% | 13 | 5 | 1 |
| APIXABAN | 21 | 0.0% | 7 | 0 | 1 |
| NATALIZUMAB | 17 | 0.0% | 10 | 5 | 0 |
| USTEKINUMAB | 17 | 0.0% | 1 | 8 | 0 |
| DENOSUMAB | 16 | 0.0% | 4 | 3 | 0 |
| HUMAN IMMUNOGLOBULIN G | 16 | 0.0% | 7 | 4 | 2 |