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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Anastomotic leak: Which Medications Cause It? (460 Reports Across 43 Drugs)

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Anastomotic leak has been reported as an adverse event with 43 different drugs in the FDA's FAERS database, with 460 total reports. 61 of these reports resulted in death.The drugs most commonly associated with Anastomotic leak are BEVACIZUMAB, CAPECITABINE, and OXALIPLATIN.

460
Total Reports
43
Drugs Involved
61
Deaths
292
Hospitalizations
56.7 yrs
Average Patient Age
42.3% / 57.7%
Female / Male

Which Drugs Cause Anastomotic leak Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
BEVACIZUMAB 109 0.1% 20 70 15
CAPECITABINE 96 0.2% 10 59 10
OXALIPLATIN 86 0.2% 8 59 21
CISPLATIN 75 0.2% 9 43 16
FLUOROURACIL 58 0.1% 4 41 18
EPIRUBICIN 35 0.2% 6 24 3
ADALIMUMAB 33 0.0% 3 20 1
LEUCOVORIN 33 0.1% 0 22 9
DOXORUBICIN 30 0.0% 2 13 9
INFLIXIMAB 24 0.0% 0 16 1
PREDNISONE 17 0.0% 1 14 1
VEDOLIZUMAB 16 0.0% 0 9 0
MYCOPHENOLATE MOFETIL 15 0.0% 1 10 5
METHYLPREDNISOLONE 13 0.0% 2 11 5
CYCLOSPORINE 12 0.0% 1 12 5
PACLITAXEL 12 0.0% 2 4 0
LEUCOVORIN\LEUCOVORIN 10 0.3% 0 9 4
USTEKINUMAB 10 0.0% 1 8 2
CETUXIMAB 9 0.1% 0 7 8
FIBRINOGEN HUMAN\THROMBIN HUMAN 9 0.9% 0 5 1

View all 43 drugs →

Top 3 Drugs Associated With Anastomotic leak

109 reports
96 reports
86 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)