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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Antiphospholipid syndrome: Which Medications Cause It? (1,143 Reports Across 100 Drugs)

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Antiphospholipid syndrome has been reported as an adverse event with 100 different drugs in the FDA's FAERS database, with 1,143 total reports. 97 of these reports resulted in death.The drugs most commonly associated with Antiphospholipid syndrome are APIXABAN, ADALIMUMAB, and RIVAROXABAN.

1,143
Total Reports
100
Drugs Involved
97
Deaths
487
Hospitalizations
49.0 yrs
Average Patient Age
71.6% / 28.4%
Female / Male

Which Drugs Cause Antiphospholipid syndrome Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
APIXABAN 116 0.1% 20 43 22
ADALIMUMAB 95 0.0% 2 26 1
RIVAROXABAN 87 0.1% 8 32 7
WARFARIN 55 0.1% 3 31 9
RITUXIMAB 41 0.0% 4 25 2
PREDNISOLONE 40 0.1% 19 26 20
INFLIXIMAB 34 0.0% 1 6 1
AZATHIOPRINE 33 0.1% 18 24 18
ENOXAPARIN 32 0.1% 1 18 5
METHOTREXATE 32 0.0% 2 11 2
PREDNISONE 32 0.0% 2 19 1
BELIMUMAB 31 0.1% 20 22 19
HEPARIN 30 0.2% 3 12 14
HYDROXYCHLOROQUINE 29 0.0% 3 10 2
ASPIRIN 28 0.0% 1 11 7
METHYLPREDNISOLONE 26 0.0% 6 18 4
ELTROMBOPAG OLAMINE 24 0.2% 1 9 3
ETANERCEPT 24 0.0% 1 10 3
MYCOPHENOLATE MOFETIL 24 0.0% 3 8 1
VALSARTAN 22 0.1% 17 18 21

View all 100 drugs →

Top 3 Drugs Associated With Antiphospholipid syndrome

116 reports
95 reports
87 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)