Aortic valve incompetence: Which Medications Cause It? (2,164 Reports Across 240 Drugs)
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Aortic valve incompetence has been reported as an adverse event with 240 different drugs in the FDA's FAERS database, with 2,164 total reports. 203 of these reports resulted in death.The drugs most commonly associated with Aortic valve incompetence are FENFLURAMINE, SACUBITRIL\VALSARTAN, and ADALIMUMAB.
2,164
Total Reports
240
Drugs Involved
203
Deaths
1,174
Hospitalizations
58.6 yrs
Average Patient Age
49.0% / 51.0%
Female / Male
Which Drugs Cause Aortic valve incompetence Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| FENFLURAMINE | 136 | 3.5% | 0 | 21 | 3 |
| SACUBITRIL\VALSARTAN | 111 | 0.1% | 6 | 65 | 1 |
| ADALIMUMAB | 106 | 0.0% | 6 | 80 | 13 |
| PANTOPRAZOLE | 80 | 0.1% | 2 | 75 | 0 |
| AMLODIPINE | 79 | 0.1% | 1 | 71 | 4 |
| BISOPROLOL | 78 | 0.3% | 0 | 53 | 0 |
| ASPIRIN | 71 | 0.1% | 1 | 57 | 4 |
| FUROSEMIDE | 68 | 0.1% | 4 | 55 | 3 |
| APIXABAN | 66 | 0.0% | 2 | 37 | 3 |
| METHOTREXATE | 65 | 0.0% | 4 | 50 | 4 |
| VALSARTAN | 65 | 0.3% | 0 | 54 | 0 |
| ROSUVASTATIN | 64 | 0.2% | 0 | 54 | 2 |
| ONDANSETRON | 53 | 0.2% | 6 | 11 | 4 |
| CARVEDILOL | 52 | 0.4% | 0 | 49 | 0 |
| TRASTUZUMAB | 51 | 0.1% | 4 | 9 | 5 |
| METOPROLOL | 50 | 0.1% | 1 | 39 | 1 |
| PREDNISONE | 50 | 0.0% | 19 | 37 | 11 |
| RAMIPRIL | 44 | 0.1% | 0 | 42 | 1 |
| TACROLIMUS | 43 | 0.1% | 4 | 33 | 5 |
| RIVAROXABAN | 42 | 0.0% | 2 | 21 | 0 |