Aplasia pure red cell: Which Medications Cause It? (1,951 Reports Across 120 Drugs)
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Aplasia pure red cell has been reported as an adverse event with 120 different drugs in the FDA's FAERS database, with 1,951 total reports. 74 of these reports resulted in death.The drugs most commonly associated with Aplasia pure red cell are DARBEPOETIN ALFA, TACROLIMUS, and ERYTHROPOIETIN.
1,951
Total Reports
120
Drugs Involved
74
Deaths
715
Hospitalizations
55.6 yrs
Average Patient Age
44.1% / 55.9%
Female / Male
Which Drugs Cause Aplasia pure red cell Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| DARBEPOETIN ALFA | 393 | 1.2% | 12 | 136 | 20 |
| TACROLIMUS | 249 | 0.3% | 2 | 92 | 15 |
| ERYTHROPOIETIN | 204 | 2.6% | 9 | 66 | 12 |
| MYCOPHENOLATE MOFETIL | 194 | 0.3% | 6 | 84 | 10 |
| METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA | 162 | 2.3% | 5 | 45 | 7 |
| PREDNISONE | 103 | 0.1% | 1 | 39 | 6 |
| PREDNISOLONE | 98 | 0.1% | 4 | 54 | 5 |
| RITUXIMAB | 98 | 0.1% | 12 | 25 | 3 |
| CYCLOSPORINE | 90 | 0.1% | 7 | 25 | 1 |
| METHYLPREDNISOLONE | 75 | 0.1% | 3 | 23 | 0 |
| NIVOLUMAB | 73 | 0.1% | 4 | 37 | 5 |
| BENDAMUSTINE | 72 | 0.4% | 1 | 20 | 0 |
| PEMBROLIZUMAB | 60 | 0.1% | 4 | 38 | 2 |
| MYCOPHENOLIC ACID | 55 | 0.3% | 0 | 9 | 0 |
| SULFAMETHOXAZOLE\TRIMETHOPRIM | 48 | 0.1% | 0 | 33 | 3 |
| AZATHIOPRINE | 47 | 0.1% | 4 | 19 | 2 |
| LINEZOLID | 47 | 0.3% | 0 | 21 | 5 |
| OBINUTUZUMAB | 46 | 0.3% | 0 | 7 | 0 |
| CYCLOPHOSPHAMIDE | 45 | 0.0% | 5 | 11 | 2 |
| FLUDARABINE | 42 | 0.2% | 4 | 3 | 0 |