Aplastic anaemia: Which Medications Cause It? (3,598 Reports Across 233 Drugs)
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Aplastic anaemia has been reported as an adverse event with 233 different drugs in the FDA's FAERS database, with 3,598 total reports. 616 of these reports resulted in death.The drugs most commonly associated with Aplastic anaemia are ECULIZUMAB, CYCLOPHOSPHAMIDE, and CYCLOSPORINE.
3,598
Total Reports
233
Drugs Involved
616
Deaths
1,616
Hospitalizations
42.3 yrs
Average Patient Age
53.0% / 47.0%
Female / Male
Which Drugs Cause Aplastic anaemia Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ECULIZUMAB | 345 | 0.8% | 40 | 133 | 7 |
| CYCLOPHOSPHAMIDE | 332 | 0.3% | 22 | 143 | 236 |
| CYCLOSPORINE | 331 | 0.5% | 64 | 111 | 43 |
| METHOTREXATE | 281 | 0.1% | 28 | 129 | 179 |
| BUSULFAN | 220 | 2.0% | 3 | 92 | 209 |
| FLUDARABINE | 220 | 0.9% | 11 | 80 | 190 |
| ETOPOSIDE | 186 | 0.4% | 5 | 96 | 122 |
| VINCRISTINE | 173 | 0.2% | 9 | 73 | 119 |
| CYTARABINE | 163 | 0.4% | 5 | 54 | 119 |
| ELTROMBOPAG OLAMINE | 149 | 0.9% | 47 | 70 | 15 |
| DOXORUBICIN | 136 | 0.2% | 18 | 45 | 85 |
| RITUXIMAB | 134 | 0.1% | 17 | 45 | 42 |
| ELTROMBOPAG | 131 | 2.4% | 56 | 45 | 10 |
| CARBOPLATIN | 130 | 0.2% | 7 | 78 | 66 |
| SOLIRIS | 120 | 5.0% | 4 | 27 | 0 |
| TACROLIMUS | 113 | 0.1% | 31 | 54 | 24 |
| ALEMTUZUMAB | 93 | 0.7% | 3 | 33 | 82 |
| PREDNISOLONE | 84 | 0.1% | 10 | 63 | 3 |
| RIBAVIRIN | 84 | 0.2% | 30 | 45 | 3 |
| TEMOZOLOMIDE | 80 | 0.5% | 35 | 33 | 10 |