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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Application site discharge: Which Medications Cause It? (914 Reports Across 22 Drugs)

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Application site discharge has been reported as an adverse event with 22 different drugs in the FDA's FAERS database, with 914 total reports. 2 of these reports resulted in death.The drugs most commonly associated with Application site discharge are INGENOL MEBUTATE, BUPRENORPHINE, and PRASTERONE.

914
Total Reports
22
Drugs Involved
2
Deaths
37
Hospitalizations
58.1 yrs
Average Patient Age
72.3% / 27.7%
Female / Male

Which Drugs Cause Application site discharge Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
INGENOL MEBUTATE 188 6.2% 0 0 0
BUPRENORPHINE 138 0.2% 0 2 0
PRASTERONE 111 7.3% 0 1 0
ESTRADIOL 72 0.2% 0 2 0
BECAPLERMIN 52 2.5% 1 6 0
MECHLORETHAMINE 45 1.7% 0 6 0
MINOXIDIL 45 0.1% 0 1 0
PICATO 31 7.8% 0 0 0
NICOTINE 20 0.1% 0 0 0
IMIQUIMOD 14 0.8% 0 0 0
DICLOFENAC 12 0.0% 0 0 0
DOCOSANOL 12 0.2% 0 0 0
SCOPOLAMINE 9 0.3% 0 0 0
COLLAGENASE CLOSTRIDIUM HISTOLYTICUM 8 0.1% 0 1 0
FLUOROURACIL 8 0.0% 0 1 0
EPOPROSTENOL 7 0.1% 1 7 0
FENTANYL 7 0.0% 0 0 1
SUMATRIPTAN 7 0.0% 0 0 0
CLONIDINE 6 0.1% 0 0 0
CRISABOROLE 6 0.1% 0 0 0

View all 22 drugs →

Top 3 Drugs Associated With Application site discharge

188 reports
138 reports
111 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)