Application site dryness: Which Medications Cause It? (2,747 Reports Across 59 Drugs)
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Application site dryness has been reported as an adverse event with 59 different drugs in the FDA's FAERS database, with 2,747 total reports. 4 of these reports resulted in death.The drugs most commonly associated with Application site dryness are MINOXIDIL, INGENOL MEBUTATE, and SUMATRIPTAN.
2,747
Total Reports
59
Drugs Involved
4
Deaths
22
Hospitalizations
51.7 yrs
Average Patient Age
52.0% / 48.0%
Female / Male
Which Drugs Cause Application site dryness Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| MINOXIDIL | 1,027 | 1.7% | 0 | 0 | 0 |
| INGENOL MEBUTATE | 365 | 12.1% | 0 | 0 | 0 |
| SUMATRIPTAN | 208 | 1.2% | 0 | 0 | 0 |
| BUPRENORPHINE | 100 | 0.1% | 0 | 0 | 0 |
| TESTOSTERONE | 63 | 0.2% | 0 | 0 | 0 |
| ADAPALENE | 60 | 0.0% | 0 | 0 | 0 |
| DICLOFENAC | 55 | 0.1% | 0 | 1 | 0 |
| ESTRADIOL | 52 | 0.2% | 0 | 1 | 0 |
| ESTRADIOL\NORETHINDRONE | 49 | 1.1% | 0 | 0 | 0 |
| NICOTINE | 48 | 0.2% | 0 | 0 | 1 |
| TRETINOIN | 44 | 1.1% | 0 | 0 | 0 |
| MECHLORETHAMINE | 40 | 1.6% | 1 | 3 | 0 |
| PICATO | 36 | 9.0% | 0 | 0 | 0 |
| DOCOSANOL | 28 | 0.4% | 0 | 0 | 0 |
| FENTANYL | 27 | 0.0% | 0 | 1 | 0 |
| METHYLPHENIDATE | 25 | 0.1% | 0 | 0 | 0 |
| KETOCONAZOLE | 19 | 0.3% | 0 | 0 | 0 |
| CRISABOROLE | 17 | 0.2% | 0 | 1 | 0 |
| ADAPALENE\BENZOYL PEROXIDE | 16 | 1.9% | 0 | 0 | 0 |
| TAZAROTENE | 16 | 3.7% | 0 | 0 | 0 |