Application site exfoliation: Which Medications Cause It? (3,254 Reports Across 65 Drugs)
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Application site exfoliation has been reported as an adverse event with 65 different drugs in the FDA's FAERS database, with 3,254 total reports. 2 of these reports resulted in death.The drugs most commonly associated with Application site exfoliation are MINOXIDIL, INGENOL MEBUTATE, and SUMATRIPTAN.
3,254
Total Reports
65
Drugs Involved
2
Deaths
44
Hospitalizations
53.9 yrs
Average Patient Age
60.7% / 39.3%
Female / Male
Which Drugs Cause Application site exfoliation Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| MINOXIDIL | 792 | 1.3% | 0 | 1 | 0 |
| INGENOL MEBUTATE | 586 | 19.4% | 0 | 4 | 0 |
| SUMATRIPTAN | 322 | 1.9% | 0 | 1 | 0 |
| BUPRENORPHINE | 143 | 0.2% | 0 | 0 | 0 |
| DICLOFENAC | 109 | 0.1% | 0 | 0 | 0 |
| PICATO | 89 | 22.3% | 0 | 0 | 0 |
| TRETINOIN | 75 | 1.8% | 0 | 0 | 0 |
| NICOTINE | 69 | 0.2% | 0 | 0 | 0 |
| ESTRADIOL | 62 | 0.2% | 0 | 0 | 0 |
| FENTANYL | 59 | 0.1% | 1 | 0 | 0 |
| TAVABOROLE | 56 | 7.9% | 0 | 0 | 0 |
| ESTRADIOL\NORETHINDRONE | 50 | 1.2% | 0 | 0 | 0 |
| ADAPALENE | 47 | 0.0% | 0 | 0 | 0 |
| MECHLORETHAMINE | 46 | 1.8% | 0 | 1 | 0 |
| TESTOSTERONE | 36 | 0.1% | 0 | 0 | 0 |
| METHYLPHENIDATE | 28 | 0.1% | 0 | 1 | 0 |
| TAZAROTENE | 24 | 5.6% | 0 | 0 | 0 |
| LIDOCAINE | 23 | 0.1% | 0 | 0 | 0 |
| SALICYLIC ACID | 23 | 1.0% | 0 | 1 | 0 |
| CRISABOROLE | 22 | 0.3% | 0 | 0 | 0 |