Application site pain: Which Medications Cause It? (17,466 Reports Across 238 Drugs)
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Application site pain has been reported as an adverse event with 238 different drugs in the FDA's FAERS database, with 17,466 total reports. 31 of these reports resulted in death.The drugs most commonly associated with Application site pain are MINOXIDIL, CRISABOROLE, and PEGFILGRASTIM.
17,466
Total Reports
238
Drugs Involved
31
Deaths
443
Hospitalizations
52.1 yrs
Average Patient Age
67.3% / 32.7%
Female / Male
Which Drugs Cause Application site pain Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| MINOXIDIL | 1,863 | 3.1% | 0 | 12 | 0 |
| CRISABOROLE | 1,414 | 18.2% | 2 | 5 | 0 |
| PEGFILGRASTIM | 1,258 | 1.6% | 1 | 15 | 1 |
| SUMATRIPTAN | 1,217 | 7.0% | 0 | 3 | 0 |
| INGENOL MEBUTATE | 1,012 | 33.5% | 0 | 13 | 1 |
| NICOTINE | 1,005 | 3.1% | 0 | 5 | 0 |
| BUPRENORPHINE | 712 | 0.9% | 1 | 9 | 2 |
| ESTRADIOL | 551 | 1.8% | 0 | 3 | 2 |
| TESTOSTERONE | 511 | 1.9% | 1 | 5 | 0 |
| DICLOFENAC | 424 | 0.5% | 0 | 8 | 2 |
| CAPSAICIN | 401 | 23.3% | 0 | 33 | 0 |
| BECAPLERMIN | 313 | 15.2% | 1 | 24 | 0 |
| FENTANYL | 302 | 0.3% | 1 | 6 | 0 |
| DOCOSANOL | 256 | 3.3% | 0 | 0 | 0 |
| MECHLORETHAMINE | 217 | 8.4% | 2 | 8 | 0 |
| ESTRADIOL\NORETHINDRONE | 173 | 4.0% | 0 | 0 | 3 |
| LIDOCAINE | 164 | 0.7% | 0 | 7 | 0 |
| METHYLPHENIDATE | 164 | 0.5% | 0 | 0 | 0 |
| MUPIROCIN | 157 | 4.5% | 0 | 0 | 1 |
| FLUOROURACIL | 145 | 0.3% | 0 | 3 | 0 |